Zodiac Spot On Plus Flea & Tick Control for Cats 5 lbs and Over 4 Pack

$13.73

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Price: $13.73
(as of Oct 24, 2025 01:31:17 UTC – Details)


Zodiac Spot On Plus Flea & Tick Control for Cats is a long lasting product specifically formulated only for cats and kittens to prevent and control flea infestations. This spot on kills fleas before they hatch which prevents flea eggs from maturing into biting adults. It also kills biting adult fleas, deer ticks, and mosquitoes your cat may acquire from its surroundings. A single application will provide egg hatch inhibition for up to 30 days.
Is Discontinued By Manufacturer ‏ : ‎ No
Product Dimensions ‏ : ‎ 5.41 x 0.88 x 4.25 inches; 0.96 ounces
Item model number ‏ : ‎ 100505298
Department ‏ : ‎ Unisex-Adult
Date First Available ‏ : ‎ October 15, 2006
Manufacturer ‏ : ‎ Central Garden & Pet
ASIN ‏ : ‎ B000HCLK1E
Best Sellers Rank: #38,172 in Pet Supplies (See Top 100 in Pet Supplies) #65 in Cat Flea Drops
Customer Reviews: 3.7 3.7 out of 5 stars 456 ratings var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });

5 in 1 control against fleas, flea eggs, flea larvae, deer ticks, and mosquitoes
1 month protection from fleas, deer ticks and flea eggs
Starts killing fleas in 15 minutes and works on contact
Monthly application for most effective protection
4-month supply

Customers say

Customers have mixed experiences with the flea and tick control product, with some reporting it works well while others say it doesn’t work at all. The product receives mixed feedback regarding flea control, with some cats still scratching themselves, and customers disagree on its effectiveness. Moreover, the product quality, value for money, and adverse effects are also mixed, with some finding it good while others say it’s not worth the price and can be harmful to cats. Additionally, the product is greasy and has a lasting chemical smell, and customers disagree on the amount of product in the vial.

8 reviews for Zodiac Spot On Plus Flea & Tick Control for Cats 5 lbs and Over 4 Pack

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  1. Kindle Customer

    I have never had a problem with this product
    I see that this product does not get good reviews which is why I am writing one. I have been using the Zodiac Spot On Plus Flea and Tick for years on my cat (he is 9yrs old now) and I have never had a problem with it. Of course I don’t wait until my cat has fleas to put it on him. I generally start in March or April depending on the weather and put the last application on in November, again depending on the weather. He has never had fleas and he has never had ticks while using this product. Although there might be a better (but more expensive) product available I continue to stick with this product because I know it works for my cat and he has never had a reaction to it. It is also reasonably priced. Yes, it is greasy, but all flea and tick products are greasy. It might hang around a little longer on his fur than other products but after a few days I have taken a wet cloth and cleaned his fur. In my opinion… pet owners should not wait until their pet has fleas or ticks to start the product. It should be started when your flea and tick season starts. Also, not all products are going to work for all pets. Fortunately for me this product works for my cat and I will continue using it until the company stops selling it. I would recommend this product to a friend.

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  2. Anne Mcarthur

    Didn’t work at all
    The medicine in this did not work at all for our Los Angeles cat Fleas all over her after 2 doses of applying. I counted nearly 50 that I pulled off with the flea comb

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  3. True Review

    Works fast and spared my cat much scratching and misery. Strong scent that cat did not like.
    My poor cat was suffering from serious flea infestation that would not go away with much flea comb use, shampooing and carpet spraying. Finally decided to try the anti-flea application (nervous about possible toxic effects on pet).Within 6 hrs cat was happy and not scratching himself to death. Three days later he occasionally scratches but when i use the flea comb maybe 1 flea at best.I could not detect significant smell but the cat clearly did not like it . Following the directions he could not-lick it off and did not want to paw it off and then lick his paws. Its nice to not have to de-flee with a comb 5x a day and still loose the battle. Most definitely recommended.

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  4. CPK

    Recommend this topical with some reservations
    Since fipronil stopped working, I have switched to several different flea remedies for the cats…each one worked for a time and then stopped as the fleas became resistant. This topical works. Not drop dead in 24 hours works, but within 48 hours there were no adult fleas, the cat shed tons of dead eggs and larvae. Highly recommend if certain other products stop working. The only downside is that some cats experience very nasty side effects from this. Their fur may fall out in patches, they may throw up, be sleepy and a little disoriented. I have not had that problem, but would recommend close observation of your cat the first few days after applying…then a nice bath to remove all dead flea debris after 4-5 days. It may work for a month or only 3 weeks. Depends on your situation.

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  5. CeceMarie

    MESSY
    This product does seem to keep the fleas & ticks; however my cats don’t go outside & didn’t have either when the product was applied. The applicators shaped like cats are cute but left a mess on my cats’ necks. The smaller of my two cats had glopped-up fur on her neck for several days. I wonder if the solution is safe for my cats to lick since it does spread past the area to which generally apply similar products.

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  6. tammy anglemyer

    Cheap and actually works
    Great price and it works

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  7. JC

    The cost isn’t worth the price
    Definitely do not recommend.I was using this product on two stray cats who make their home in my backyard. I’ve worked in stray rescue and care for 7 years, and had my own pet cats my entire life. Additionally, I read directions. Always. The third month of treating I noticed one of the cats acting like I was going to hurt him and he refused to be treated, his normally very friendly behavior becoming hissy and he eventually bolted. I was petting the other cat a few days later and noticed he’d developed scabs where he’d been treated. I immediately washed off the remaining residue on his fur and skin and treated the area with chlorhexidine for a week to heal it up.

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  8. Sara Elizabeth Smith

    THIS STUFF WORKS
    This is the only kind I buy and it works wonderfully. I take care of stray cats that are well, mine now, and they had fleas and ticks especially being outside cats most of the time. It works really quick and I saw dead ticks on the floor that I didn’t even know were on the cats since I checked them every day. But with all animals, they’re different, so what works for my animals might not work for yours. I care for 8 stray cats and none have had a reaction to it which is really important because I didn’t use another certain brand due to hearing about all the interactions on cats skin due to that certain brands products. I know two people personally who had a cat with a bad reaction to hartz guard. So guard yourself….I recommend this because it is SPOT ON. 🙂

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    Zodiac Spot On Plus Flea & Tick Control for Cats 5 lbs and Over 4 Pack
    Zodiac Spot On Plus Flea & Tick Control for Cats 5 lbs and Over 4 Pack

    $13.73

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