Seachem Prime Fresh and Saltwater Conditioner – Chemical Remover and Detoxifier 500 ml
Original price was: $21.40.$13.44Current price is: $13.44.





Price: $21.40 - $13.44
(as of Oct 11, 2025 13:36:23 UTC – Details)
Prime is the complete and concentrated conditioner for both fresh and salt water. Prime removes chlorine, chloramine and ammonia. Prime converts ammonia into a safe, non-toxic form that is readily removed by the tank’s biofilter. Prime may be used during tank cycling to alleviate ammonia/nitrite toxicity. Prime detoxifies nitrite and nitrate, allowing the biofilter to more efficiently remove them. Prime also promotes the production and regeneration of the natural slime coat. Prime is non-acidic and will not impact pH. Prime will not overactivate skimmers. Use at start-up and whenever adding or replacing water. As part of their ongoing environmental stewardship efforts Seachem will donate a portion of the profits for every specially labeled edition bottle of Prime, Stability, Pristine, and Clarity (in Bonus Sizes of 325 mL — 30% more) sold to a Rhino preserve in South Africa.
Is Discontinued By Manufacturer : No
Product Dimensions : 6.6 x 2.5 x 2.3 inches; 9.92 ounces
Item model number : 67104330
Department : men, women
Date First Available : June 20, 2004
Manufacturer : Seachem Laboratories, Inc.
ASIN : B00025694O
Best Sellers Rank: #624 in Pet Supplies (See Top 100 in Pet Supplies) #1 in Aquarium Water Treatments
Customer Reviews: 4.8 4.8 out of 5 stars 40,158 ratings var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
POWERFUL TREATMENT: Seachem Prime is a complete and concentrated conditioner for both freshwater and saltwater fish tanks, working hard to remove chlorine and chloramine.
REMOVER: Seachem Prime immediately and permanently removes chlorine and chloramine, successfully allowing the bio filter to remove ammonia, nitrite, and nitrate while they are detoxified for 48 hours.
DETOXIFIER: Seachem Prime effectively detoxifies ammonia, nitrite, and heavy metals found in the tap water at typical concentration levels, providing a ideal environment for your betta, tetra, or other fish.
USE: Use 1 capful (5 mL) of Seachem Prime for each 200 L (50 US gallons) of new or replacement water. For best results, add Seachem Prime to new water first. For exceptionally high chloramine concentrations, a double dose may be used safely. For smaller volumes, use 2 drops per gallon.
SAFETY: In case of an emergency, the 5x dose of Seachem Prime may be used for both ammonia and nitrite. Use a ½ dose if the water temperature is > 30°C (86°F) and chlorine or ammonia levels are low.
Customers say
Customers find this water conditioner to be the best on the market, noting it works instantly and effectively removes ammonia, chlorine, and detoxifies nitrite and nitrate. Moreover, the product lasts through many water changes and keeps fish healthy and happy, making it a must-have for both freshwater and saltwater tanks. However, some customers mention it has an awful smell.
8 reviews for Seachem Prime Fresh and Saltwater Conditioner – Chemical Remover and Detoxifier 500 ml
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Original price was: $21.40.$13.44Current price is: $13.44.
Alicia –
20+ Years of Flawless Performance!
As someone who’s been deeply involved in the aquarium hobby for over two decades, I can confidently say that Seachem Prime is, without a doubt, the single most essential product in my fish room. I was introduced to Prime when I first started out, and it quickly became the cornerstone of my water care routine. Twenty-plus years later, it remains the only water conditioner I trust and use in all my tanks.Prime does exactly what it promises, and it does it exceptionally well. It instantly neutralizes chlorine, chloramine, and ammonia, making tap water safe for your aquatic inhabitants. Beyond that, it detoxifies nitrite and nitrate, which is a huge bonus, especially during cycling or in emergency situations. The fact that it does all of this in a concentrated formula means a little goes a very long way, making the 1L bottle incredibly economical and long-lasting.What truly sets Prime apart, for me, is its reliability and the peace of mind it provides. I’ve never had a single issue with water parameters or fish health that could be attributed to Prime. It’s truly a “set it and forget it” product that allows me to focus on the joy of the hobby rather than worrying about water quality.If you’re new to the hobby, do yourself a favor and start with Prime. If you’re a seasoned aquarist looking for the best, you already know what I’m talking about. I exclusively use Seachem products in my tanks because their quality and effectiveness are unmatched, and Prime is the shining star of their lineup. This isn’t just a water conditioner; it’s an investment in the health and longevity of your aquatic ecosystem. Five stars, hands down!
James Williams –
Great product
From Cichlids to Fancy Goldfish I’ve been keeping fish for 30+ years.Just about every major manufacture and boutique specialty company has a water conditioning and treatment product.I can’t say I’ve tried them all, but close too it. Some products have at the least, minimal effectiveness while others can be potentially dangerous.An example would be Stress Coat which has binding sugar strands in the Aloe. This isn’t a problem unless one of your fish has a small scratch or wound.The sugar feeds the bacteria which can lead to major infection and dire consequences.I’ve been using Amquel for years and it’s a fine conditioner, excellent at removing chlorine, and Chloramines, but like all these products – they come with limitations.Well, with one exception and that’s Prime by Seachem.A few months ago, I decided to give it a try, and haven’t looked back since. Prime doesn’t just remove the chlorine and Chloramine it does much more:* Detoxifies any and all heavy metals in your tap water(you can call your water company directly for a list of them and PPM)* Neutralizes Ammonia* Neutralizes Nitrite* Neutralizes high Nitrate to non toxic levels* Removes toxic gases* Will not foam or change PH* Helps regenerate natural slime coatSince using Prime, I’ve seen a dramatic improvement in all of my fish. In 2010 one of tanks was hit with the dreaded and rare Toxic Tank Syndrome – within 48 hours I had lost nine gorgeous fish – except for one survivor, a single Broad Tail Nymph.Since that ordeal, “Roxy” became a bottom dweller spending most of her time laying in a corner. Treatments were conservative, but nothing worked.After my first 50% water change using Prime her behavior began to improve. Now she swims among her tank mates, her color is better, gill movement stabilized and her appetite ferocious. In fact I see improvements in all my fish and in every tank.There simply isn’t anything like it, Prime is hands down one of the best things you can do for your fish.In addition to the outstanding, patented formula of Prime – it couldn’t be more economical to use. A single 500 ml bottle treats up to a whopping 5,000 gallons of water. A tiny bit goes a long, long way.It should also be noted that in times of emergency the dose can be increased five times, Prime is harmless to fish.It’s the only product of it’s kind, and towers above any other water treatment on the market – period.If your an aquarium hobbyist be it novice or advanced – I would urge you to add a bottle of Prime to your arsenal of fish care products. Your finned friends will thank you for it.
Misty –
ð§ Saved My Bettaâs Tank â Fast, Easy, and It Works!
I bought this aquarium water conditioner for my Betta fish tank after struggling to get the water levels just rightâand it made a huge difference! I was seeing numbers all over the place with my test kit, and this product helped stabilize everything quickly.Itâs super easy to useâjust a few drops, and you’re good to go. Within a short time, the water parameters were back in the safe zone, and most importantly, my Betta is still happily swimming and looking healthier than ever.No weird smells, no cloudiness, just clean, conditioned water thatâs safe for my fish. If youâre new to aquariums or just having trouble balancing your water, this is a great product to keep on hand.
Slade. –
Produto com 50ml da Prime referencia em qualidade para o ramo do aquarismo.Remove cloro, cloramina e amônia, super concentrado podendo tratar 4 litros com apenas 2 gotas do produto.
marco antonio ramos –
Prime de Seachem es, sin duda, uno de los mejores acondicionadores de agua del mercado. Neutraliza instantáneamente cloro, cloraminas y amonÃaco, lo cual es esencial tanto en cambios de agua como en emergencias. Además, ayuda a proteger a los peces reduciendo el estrés y facilitando la desintoxicación de nitritos y nitratos.Rinde muchÃsimo: solo se necesita una pequeña dosis por litro, lo que lo hace muy económico a largo plazo. Lo uso en todos mis acuarios y ha sido clave para mantener a mis peces sanos y el agua en perfectas condiciones.Recomendado al 100%, sobre todo si buscas seguridad y estabilidad para tus peces.
Nicolas –
Le produit a un réel impact sur les analyses d’eau, très efficace à petite dose. Seul aspect dérangeant: son odeur de soufre à l’ouverture de la bouteille. Mais une fois dans l’eau ça ne sent rien.J’ai reçu par contre une bouteille abimée, l’embouchure était tordue et une fois enlevé l’opercule, l’étanchéité était compromise, j’ai dû transvaser le produit dans une autre bouteille.
Joshua Meade –
The prime cleans up the slime! It is so divine, you’ll certainly not mind the word on the vine is this stuff is sublime! Make sure to choose prime, for your brine!
sarah buller –
Great product and such a small amount required at water change.Highly recommended. I used for my newly hatched Axolotl and also my tropical fish tank.