Ortho Home Defense Insect Killer for Indoor and Perimeter2 with Comfort Wand, Controls Ants, Roaches, Spiders and More, 1.33 gal
$25.99










Price: $25.99
(as of Oct 22, 2025 12:45:03 UTC – Details)
Ortho Home Defense Insect Killer for Indoor & Perimeter2 kills common household bugs such as ants, beetles, centipedes, cockroaches, crickets, fleas, flies, millipedes, mosquitoes, moths, spiders, stink bugs, ticks, termites, periodical cicadas and more (as listed). This insect killer creates a bug barrier for up to 12 months protection against ants, roaches and spiders indoors on non-porous surfaces. In addition, the Invisi-Shield Technology formula gives off no fumes, dries clear and dries fast. Use this pest control product anytime as a preventative treatment or after you see evidence of insect activity for long lasting-control. Apply indoors in kitchens and bathrooms or around doors and windows, and outdoors to the foundation perimeters, patios, decks, garages and wherever insects are a recurring problem. The included continuous spray Comfort Wand makes application easy without bending, pumping or hand-fatigue. For indoor surfaces, hold sprayer 12 inches from surface being sprayed and apply a 4-inch wide band, or use a 12-inch wide band when applying to a home perimeter. Area should be sprayed until slightly wet without soaking. People and pets may re-enter the treated area once sprays have dried. Trust Ortho to keep bugs out of your home.
Ortho Home Defense Insect Killer for Indoor & Perimeter2 kills the toughest home-invading insects, including ants, cockroaches, spiders, fleas, ticks, scorpions, earwigs, silverfish and periodical cicadas (as listed)
This insect killer spray provides a long-lasting bug barrier of up to 12 month protection against ants, roaches and spiders indoors on non-porous surfaces
Use this pest control spray indoors in kitchens and bathrooms or around doors and windows, and outdoors to the perimeter of foundations, patios, decks, garages or wherever insects are a recurring problem
Apply this bug killer anytime as a preventative treatment or after you see evidence of insect activity
This 1.33 gal. container of Ortho Home Defense Insect Killer for Indoor & Perimeter2 comes with a battery-powered Comfort Wand, which delivers a continuous spray for easy application
Customers say
Customers find the insecticide effective at killing ants, roaches, and spiders, and appreciate its ease of use, particularly the comfort wand applicator. The product is odorless and offers good value compared to pest control services. However, the functionality and longevity receive mixed reviews – while some say it works instantly and lasts a year, others report it doesn’t work at all and doesn’t last as long as advertised. The spray effectiveness is also mixed, with several customers reporting issues with the sprayer not working properly.
10 reviews for Ortho Home Defense Insect Killer for Indoor and Perimeter2 with Comfort Wand, Controls Ants, Roaches, Spiders and More, 1.33 gal
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$25.99
Melissa –
Hogar
Very effective and easy to use!Iâve used Ortho Home Defense several times, and it really works great. It kills ants, roaches, and spiders quickly, and keeps them from coming back for weeks. I like that it doesnât have a strong smell and dries fast, so I can spray it inside the house without any problem. The wand makes it super easy to apply around corners and baseboards. Definitely worth the price â I feel my home is much more protected now!
shopper. –
IT WORKS VERY WELL – IF YOU USE IT CORRECTLY
This is a solid product.This is not designed for infestations or ant hills. It is a product designed to prevent entry of insects into your residence and eliminate individual insects that have entered. While this may help the odd case of colonized insects, it really is made for those solo runners that snuck in when you weren’t looking.If you have an infestation or a mess, your insects are doing more than entering your house, they are living in it. Perhaps if it was sprayed around the house like the floors were being watering your floors it would work on infestations…but, PLEASE DON’T DO THAT, it wasn’t designed for that use nor was that dosage tested for human/animal exposure. Consider calling an exterminator for infestations (100s+, colonies, groups of insects, etc.). And as for ant hills, either remove them, or buy poison for ant mounds. Are there ant hills in your home? That seems like a different problem.After you’ve taken care of cleaning things up, then protect your residence from the entry of new insects. You’ll see this product is WONDERFUL FOR THE JOB. I’ve used it for years, one home in a very wooded, shaded area, one home in the south. Works like a charm…spraying as others have mentioned…seasonally.This product works by leaving a residue, so if what you spray it on (baseboard, perimeter of home covered in leaves in the fall, edge of home outside, etc.) is cleaned, blown away, excessively rained on…some or all of that residue will be removed…particularly overtime. Be aware of your specific situation and adjust your application frequency accordingly.IF YOU CREATE A BARRIER, THEY WILL NOT ENTER. (Read the label for all the insects covered…it’s extensive.)1. Clean up your outside and inside space a little of non-permanent items, pulling things from the perimeter (toys, anything that shouldn’t be on the floor or ground basically). Eliminate debris and items in which insects hide, make webs, etc.2. Spray the OUTSIDE perimeter and along the border of every door and window.3. Spray the INSIDE perimeter, along the base boards, of your whole house (closets, pantries, bathrooms included). Then spray a barrier between rooms (around the door frame).Lastly, I understand the frustration that might occur if your wand or applicator never came. Exchange it with Amazon, try a spray bottle, etc.I’ve been using this with pets. Label says that IT MUST DRY BEFORE IT IS OK WITH PETS. Please remove them from the area while you apply. If you have a pet roach or tarantula I don’t know what to tell you.All the best, and good luck with your application.
RG –
Excellent at keeping bugs away!
We have been using Ortho Home Defense for years. It’s the most effective and safe insect killer we have used to date. It doesn’t have a strong smell and doesn’t leave any sticky residue. We had not had any leakage issues either with the nozzle. This product has been a consistent for us and never lets us down. The length of time between sprays is about every six months or so. Very easy to use! Excellent value. We spray outside and inside with this and works well.
Gregory Dornbush –
Effective Pest Control with Minor Drawbacks
Ortho Home Defense Insect Killer is a reliable solution for keeping common household pests at bay. It effectively targets ants, roaches, spiders, and other listed insects, providing long-lasting protection when applied correctly.The Home Depot+4YouTube+4Amazon+4â Pros:Effective Pest Control: Kills a wide range of insects, including ants, roaches, spiders, fleas, ticks, scorpions, beetles, silverfish, centipedes, and millipedes.Long-Lasting Protection: Provides up to 365 days of protection on non-porous surfaces.Ease of Application: Comes with a Comfort Wand that allows for easy application without bending or pumping.AmazonAmazon+1The Home Depot+1â ï¸ Cons:Mixed Results on Effectiveness: Some users have reported that the product is less effective on certain pests or in specific conditions.Battery Operated Wand Issues: A few customers have experienced issues with the battery-operated spray wand, including short battery life and inconsistent spray patterns.The Home Depot+1The Home Depot+1ð¡ Tips for Best Results:Apply to Entry Points: Focus on spraying around doorways, windows, and other potential entry points to create a barrier against pests.Reapply as Needed: While the product offers long-lasting protection, reapplication may be necessary in areas with high pest activity.The Spruce+7Ortho+7Reddit+7Final Verdict: Ortho Home Defense Insect Killer is a solid choice for homeowners seeking an effective and easy-to-use pest control solution. While there are some minor drawbacks, its overall performance and convenience make it a worthwhile option for maintaining a pest-free home.
Dunia –
Works well!
I used this around my house and it really helped keep ants and bugs away. The spray wand is easy to use and reaches corners nicely. No strong smell, and it dries fast. So far, it’s doing a good job!
Abdullah –
Effective
Beverley –
Have used this product before in the Caribbean. No roaches or the like for 5 years so I know it works. Pretty hefty price tag though for shipment to the UK when much lower price on the other side of the pond. But the heart wants what the heart wantsâ¦
Keith G –
Really great stuff. Keep bugs away for weeks
user-MGL9Q6 –
٠٠تاز
Ritz Leosala –
Cockroaches become more healthy no one told me that this is a vitmins for cockroaches such a waste of money never buy