K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 2-Mo Supply
$35.68
Price: $35.68
(as of Nov 02, 2025 17:52:50 UTC – Details)
K9 Advantix II Extra Large Dog is the veterinarian-recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult fleas on contact so they can’t lay eggs and they don’t have to bite your dog to die. Fleas, ticks, mosquitoes and other pests not only cause discomfort; they may also transmit disease. Monthly use of K9 Advantix II is important to protect your dog against fleas that may cause transmission of tapeworms. This formula also kills fleas which may cause Flea Allergy Dermatitis and flea bite anemia. That’s why K9 Advantix II Extra Large Dog topical, spot-on formula makes application simple – going on in seconds. It’s easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that K9 Advantix II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. K9 Advantix II pest protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh over 55 lbs. to use K9 Advantix II Extra Large Dog. For the ultimate convenience in care, K9 Advantix II is available over the counter – no prescription needed. And, you can stock up with 2-dose, 4-dose and 6-dose packs so you never miss a monthly treatment. Once K9 Advantix II is applied, your dog is ready to get right back to big-pup cuddles and racing around the park. K9 Advantix II Extra Large Dog is a trademark of Elanco or its affiliates.
Is Discontinued By Manufacturer : No
Product Dimensions : 1 x 4.38 x 4.75 inches; 1.13 ounces
Manufacturer recommended age : 1 month and up
Item model number : 86314819
Department : Flea & Tick
Date First Available : January 23, 2014
Manufacturer : Elanco US Inc
ASIN : B00I0BWNUG
Best Sellers Rank: #223 in Pet Supplies (See Top 100 in Pet Supplies) #3 in Dog Flea Drops
Customer Reviews: 4.4 4.4 out of 5 stars 47,216 ratings var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
K9 Advantix II Extra Large Dog 30-day treatment & prevention protects dogs over 55 lbs. from fleas, ticks, mosquitoes, biting flies and lice
Kills fleas within 12 hours of application
Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
No prescription needed
Customers say
Customers find this pest control product effective and easy to apply, noting it’s better than Frontline and provides good protection against fleas, ticks, and mosquitoes. The product quality receives positive feedback, and customers appreciate its ease of application compared to pills. However, experiences with effectiveness and flea control are mixed – while some report no fleas or ticks, others say their dogs still pick them up. Skin irritation and side effects also show mixed results, with some customers reporting no issues while others experience itching and sickness. Value for money opinions are divided between those who find it great for the price and those who consider it not worth the money.
6 reviews for K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 2-Mo Supply
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$35.68
ARBONNE –
Works great awesome I definitely suggested
UPDATEI donât know what yâall all your people take your dogs to the vets instead of showing them online here that they canât walk. The fur is falling out of the bleeding. Thatâs ridiculous. Take your dog to the friggin neck. Let the vet determine the cause exactly and then if itâs in clause because of this then Put a negative and state the fact that you took him to a vet and the vet did test and it was the closet because Iâve been using this product for 25 years on my dogs back then and my new dogs now my dogs I had 16 years ago dogs I had 10 years ago dogs I had 13 years ago my 16 1/2 year old cocker spaniel has had this from the day he could actually have this And I have never had a problem with that on any of my dogs especially him you know it got rid of the fleas and I noticed a few texts very easy to get off compared when I didnât use it like if I skipped a couple of months and they had a dick and I was like oh my God and then I would try to get it off and it was a hassle. I mean, it did not pull up. Come out whatever And so I put them back on this every month originally and if they get a tick and I see it. I just need tweezers and it just pops right off no eggs inside nothing no problem with the weather did not cause any of my dogs ever itch or lose hair so I think you people have an undergoing problem with your dog that you did not address Prior to use this. Yes, Iâm gonna blame you. Yes Iâm blaming all you that people that has undermining problems with their dog and you donât take them to the vet and you add this product on top of them. Yes, it probably will do something like that.SO I REPEAT, TAKE YOUR DOG TO THE GD VETERINARIAN PROFESSIONAL LET THE PROFESSIONAL DO THEIR WORK !!!!Oh, I also have one dog right now. I have three of them English mastiff and I have one of them that sits at my back gate in the dirt never has fleas never has sticks never has any. He lays in the dirt 185 pound and his head I can look it out right now his head is in it. His whole body lengthwise is in it and I swear he digs holes just you know it makes it cool.. and thereâs a picture of him laying at the fence in the dirt. He loves it. I check them every day. Nobody has fleas. Nobody has anything so you people are doing something wrong. Iâm gonna blame all of you. They have a problem and Iâll say it again again again they have underlining problem TAKE THEM TO THE VET VETERINARIAN HAVE THE VET, VETERINARIAN, TECHNICIAN, AND DOCTOR EXAMINE THE DOG TAKE SKIN GRAPHS WHATEVER THE BEST HAS TO DO. DONâT BLAME THE PRODUCT UNLESS YOU DID THAT AND IF YOU DID IT AND THEN DOCTOR RUNS TEXT AND SAID YES, IT WAS CAUSED BY THAT PRODUCT. WELL HENCE THERE YOU GO AND ITâS THE PRODUCT FAULT BUT A 99.999% ITâS NOT THE PRODUCT.Started having dogs when we first got married we have we had seven English mastiffs yeah itâs addicting and they had puppies and everything so anyways Iâve been using this on my dogs from year 2000 and I use them before that on my other dog so Iâve always used it really and I love it. I mean, I swear by it this stuff is great. My dogs do not get flea or I mean I have to put a spray on them to detail the mosquitoes, but donât see my bugs biting them. Itâs pricey, but itâs worth it. You donât wanna have your dogs get Lyme disease or you know from ticks, I really suggest this.No bother my dog knock on wood you know in the other thing is I donât use this year around. I only use it from spring until after fall. I donât feel I really needed in the winter time. Itâs too cold outside for anything to live so Iâm up Northeast And I donât seem to have any problem and theyâre not using it as soon as spring hits thatâs that boom theyâre on it.
yishin –
The safest and most effective tick protection – ticks fall off just from touching the fur
I brought my dog to West Virginia, and thank God for Advantix II â because Iâve been finding half-dead ticks every single day (no joke) in places where she sleeps or rests. At first, I was confused. I thought “repels ticks” meant it would work like bug spray does for mosquitoes, keeping them away completely. But after looking into the active ingredient, permethrin, I realized that in this case, ârepelâ means: once a tick touches the treated fur, it becomes so irritated or neurologically impaired that it canât bite, canât hang on, and eventually just falls off and dies.Thatâs still so much better than PetArmor, Frontline, or any of the oral preventatives (like Simparica or NexGard), which require the tick to bite the dog before it dies. No thanks. Every tick Iâve found so far had already dropped off my dog before it had a chance to bite her and feed â exactly what you want in a tick-heavy area.Iâve also tried Wondercide (cedar oil). It works okay for fleas, but itâs just not effective for ticks, especially not in the long term. Its protection wears off after 2â4 hours. I learned the hard way â my dog caught Lyme disease, developed joint pain and a limp. Thankfully, doxycycline helped and sheâs okay now, but it required a full 28-day antibiotic course.I would never use oral flea/tick medications. Just ask around â youâll hear plenty of stories about dogs having seizures after taking them. For me, that risk isnât worth it.If you have a cat at home, unfortunately Advantix II may not be right for your household â permethrin is toxic to cats (especially when wet). But if you donât have cats, I highly recommend this product to all dog owners. Tick-borne diseases are no joke. Fleas are annoying â Iâve had to go through the nightmare of clearing an infestation â but at least they just suck blood without causing life-threatening illness.Ticks, on the other hand, can transmit Lyme, Ehrlichia, Rocky Mountain spotted fever, and more. So if you live somewhere warm, humid, grassy, or deer-heavy â do your dog a favor and get Advantix II. Itâs been a lifesaver for us.
Dejavulove –
Awesome product totally worth it
My dog has no fleas and I have a husky. This actually works really well.
Karla L. Ferguson –
OK, but not perfect
Works OK, but I still have some flea issues. No tick issues though.
Amber Tamplain –
Amazing relief for my dogs.
Iâm honestly in shock at how well Advantix Tick and Flea works! We live in a farm and it’s hard to control these pests. My dogs have been so calm and comfortable since using it , no more scratching, biting, or restlessness. It started working fast, and I could see a huge difference right away. Iâve tried other products before, but this one really stands out. Iâll definitely continue to use it. Highly recommend for any dog owner who wants quick and effective relief for their pets!
CCCorbett –
Only thing that works
K9 Advantix 2 is the only thing that works for the itchy bugs here in Oklahoma. This is a 2 pack for XL dogs. I bought it for my corgis, splitting one tube between them (they’re 30lbs each). I find it to be a much more cost effective way of treating them. Easy to use, simply run the open tube up their spine from tail to collar. Just avoid giving them a bath for a few days. Product doesn’t work “instantly”. It takes a day or two to kick in.