DrTim’s Aquatics First Defense for Koi Pond and Water Gardens – Stress Relief & Immune System Support with Vitamins & Immunostimulants for Fish Ponds 16oz – Treats 960 gal
Original price was: $23.09.$20.69Current price is: $20.69.





Price: $23.09 - $20.69
(as of Oct 31, 2025 02:56:08 UTC – Details)
Product description



DrTim’s Aquatics makes 100% natural products for freshwater, saltwater, and reef aquariums and Koi ponds and water gardens like One & Only Live Nitrifying, Eco-Balance Probiotics, Waste-Away sludge busters, and First Defense stress reducer. We offer a variety of products to successfully start up and maintain fish tanks and aquariums of all types and sizes. DrTim’s products are developed in the USA and all packaging is 100% recyclable.
DrTim’s Aquatics First Defense for Koi Ponds and Water Gardens
Stress Relief & Immune System Support
DrTim’s Aquatics First Defense provides stress relief and naturally supports fish immune systems. Our formula contains a mixture of vitamins and immunostimulants that promote wound healing and reduce stress caused by poor water quality conditions. DrTim’s Aquatics First Defense also contains a slime coat replacement substance, which will promote healing and repair wounds.
Provides natural stress relief to fish Naturally supports fish immune system Contains vitamins and immunostimulants Revitalizes the natural slime coat on fish Detoxifies heavy metals in water

Reduce Stress in Your Pond
All animals including fish, shrimp and turtles react to stress in similar ways that humans do. Stress can weaken their immune systems and reduce their ability to fend off illness, resulting in poor health and body condition and loss of color. Minimizing and removing stress agents in the pond is critical to ensuring the health and well-being of all aquatic creatures by reducing the opportunity for harmful bacteria to grow and spread.
Changes to a fish’s environment can cause stress that robs them of essential nutrients and can weaken their immune system. Leading causes of stress on fish and other aquatic organisms is poor water quality, bagging and shipping from the store to your pond, water changes, and new fish additions. DrTim’s Aquatics First Defense is scientifically designed to provide stress relief and naturally support fish immune systems with vitamins and immunostimulants. For best results, use during new pond set-up, when adding new fish, and after routine pond maintenance.

First Defense contains a mixture of vitamins and immunostimulants that work together to help fish and other aquatic organisms adapt and cope when introduced to new environments and stress that can occur with poor water quality conditions. Consistent dosing after environmental changes is your first line of defense to support fish health, while also promoting healing and wound repair.

DrTim’s Aquatics First Defense works to provide nutrients that boost the immune systems of fish and aquatic creatures by neutralizing chlorine and chloramine, buffering against pH level changes, and detoxifying heavy metals. Our formula should be added to the pond during water changes and at any point when fish are showing signs of stress.

We recommend using a minimum dose of 1 ounce (30 ml) per 60 gallons of water during new pond set-up, when adding new fish, with every water change, and after routine pond maintenance. *Caution: DO NOT add First Defense on the same day as Eco-Balance or Waste-Away.

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Customer Reviews
5.0 out of 5 stars 1
4.6 out of 5 stars 165
4.4 out of 5 stars 598
4.1 out of 5 stars 332
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4.5 out of 5 stars 671
Price
$48.77$48.77 $28.11$28.11
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$66.95$66.95
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Product Size
16, 32, 64 & 128oz 16, 32, 64, & 128oz 16, 32, 64, & 128oz 16, 32, 64, & 128oz 16, 32, 64, & 128oz 16, 32, 64, & 128oz
Amount of Water Treated (gal.)
480, 960, 1920 & 3840 960, 1920, 3840, 7680 960, 1920, 3840, 7680 960, 1920, 3840, 7680 960, 1920, 3840, 7680 480, 960, 1920, 3840
Benefits
Lowers nitrates and phosphates, unclogs and cleans rock beds, removes gunky & hidden wastes, dissolves sludge, & keeps filter pads cleaner, longer Eliminates common chemicals in tap water & removes chlorine, chloramines, and ammonia Helps fish adapt to new environments with a mixture of vitamins and immunostimulants Clears up cloudy, white water without chemicals Revitalizes old, green/brown water & keeps water odor free Maintains a balanced, healthy pond environment, blocks out unfriendly bacteria, & promotes optimal water quality
Usage
Use once per week as a natural way to keep your pond clean. Before setting up a new pond When doing partial water changes, during treatments and when fish are showing signs of stress When water starts to become cloudy/white When water starts to become brown/green Use on a weekly basis to restore and maintain a clean, balanced, healthy pond
Product Dimensions : 4 x 1.75 x 6 inches; 1 Pounds
Item model number : 623
Date First Available : June 8, 2005
Manufacturer : DrTim’s Aquatics, LLC
ASIN : B0027J8MYS
Best Sellers Rank: #119,325 in Pet Supplies (See Top 100 in Pet Supplies) #1,051 in Aquarium Water Treatments
Customer Reviews: 4.4 4.4 out of 5 stars 598 ratings var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
First Defense for Reef Aquarium provides stress relief & naturally supports fish immune system
Aids corals, fish & other aquatic organisms as they adapt to new tank environments & poor water quality conditions
Contains a mixture of vitamins & immunostimulants that promote wound healing & boost immune health
Neutralizes chlorine & chloramine in water, buffers against pH changes, & detoxifies heavy metals
Use when setting-up a new aquarium, changing tank water, adding new fish & after routine maintenance
Customers say
Customers find the water treatment effective at keeping fish healthy and appreciate its quality. Moreover, the product helps reduce stress on fish, with one customer noting their fish appear visibly more relaxed. However, customers report issues with excessive bubbles in the skimmer, and there are mixed opinions about the product’s appearance.
13 reviews for DrTim’s Aquatics First Defense for Koi Pond and Water Gardens – Stress Relief & Immune System Support with Vitamins & Immunostimulants for Fish Ponds 16oz – Treats 960 gal
Add a review
Original price was: $23.09.$20.69Current price is: $20.69.
jason –
good
goodãVery good product
Gerard Dube –
It works perfect.
Worked in 2 weeks using their Ammonia.
Weather watcher –
Slow delivery
The product seems to work, however, it was very slow in coming. If you need it now, you best have it on the shelve.
Amazon Customer –
Is a bottle of potent anti anxiety,antibiotics,anti inflammatory med for fish.
Had a Cory with fin tear.Began to bleed & look really bad.Loss of mate caused anxiety swim & overuse.After looking at the uses for Dr Timâs Stress relief and immunity boost had to try.OMG!! Added recommended amount to tank & in 3-4 hours she calmed down and was visibly so much more relaxed.Swim mania stopped and 2 days later her fin was completely healed!Just stunned!This is literally Xanax for fish and antibiotic/anti inflammatory treatment.Stops post water change anxiety also.Just PRICELESS!I will never let my fish be without! Also stops postwater change agitation.
R013 –
Reliable product
Iâve been using this consistently in my 11 gallon reef tank after having some sludge build up with great results. I usually add it every time I do a water change and can definitely see the results.
Kelly Glinski –
Works Well
I did quite a bit of work to my pond including several water changes. This product definitely helped to reduce the stress on my fish.
AV19 –
Now with super foaming action!…
Makes your protein slimmer completely in usable, so you better have other nutrient control measures in place. Luckily my refugium is up to the task of serving as sole filtration.I did a half dose once, left the skimmer off for six hours like they recommend. And when I turned it back on it instantly foamed over. I figured ok give it 24hrs, no change, 48, 72, still no change instant foam. But my refugium is doing great keeping everything in check so I let it go for over a week, still foam crazy. So I do a 20% water change, still foams over. It took 2, 50% water changes so I could use my slimmer again.The fish do look pretty nice and happy so it wasnât a complete waste, just wish they were more upfront about what it was going to do to my system.
Diverdown1 –
Works Like Magic
This stuff is amazing cleared out my Cyano and tank is super clean.
Amazon Customer –
it keep my fish healthy. Recommend using with interval water change
MusicSound –
Not sure about this stuff as recommended dose first time 2 fish losses so been using lesser dose.
Mina –
Not sure what’s in this liquid to make it that Blue color I thought it would be clear. Secondly it doesn’t come sealed like most Tims products, at least my 4 oz bottles were not sealed other than the cap… I don’t feel very comfortable with that plus i feel like it didn’t do nothing for my water quality.
Przemek Kwiatkowski –
Great product
Julius –
Great product