Douxo S3 SEB Shampoo, Contains 0.5% Ophytrium, Odor Control & Seboregulating, for Oily to Flaky Skin, Seborrhea, for Dogs and Cats, 6.7 fl. oz. (200mL)
$22.99








Price: $22.99
(as of Nov 04, 2025 13:59:43 UTC – Details)
Formulated to remove excess sebum, oils and flaky skin buildup. Helps reduce dandruff and deodorize. Moisturizes and detangles the fur to leave the coat soft and shiny. DOUXO is the 1 non-prescription topical brand used and recommended by U.S. veterinarians for dogs and cats with seborrheic dermatological diseases.
Product Dimensions : 2.01 x 2.72 x 6.06 inches; 8.82 ounces
Item model number : D98610P
Date First Available : November 1, 2020
Manufacturer : Douxo S3
ASIN : B09477RPFH
Best Sellers Rank: #9,595 in Pet Supplies (See Top 100 in Pet Supplies) #78 in Dog Shampoos
Customer Reviews: 4.6 4.6 out of 5 stars 794 ratings var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
DOUXO S3 SEB Shampoo is for dogs or cats with oily to flaky skin
Helps control dandruff and odor by normalizing sebum production while hydrating the skin
Detangles the fur and leaves the coat soft and shiny
Clinically proven in dogs to reduce dandruff, excess sebum, and unpleasant odors
For best results use with DOUXO S3 SEB Mousse
Customers say
Customers report that the shampoo works wonders for their pets’ skin, with one mentioning it’s particularly effective for dogs with greasy hair. Moreover, the product receives positive feedback for its scent, with customers noting it smells better, and its effectiveness in reducing skin irritation, with one customer reporting no more scratching or flaky skin. Additionally, the shampoo makes dogs’ fur soft after drying, and customers find it to be of good quality. However, opinions are mixed regarding value for money, with some finding it a great value while others say it’s pricey for the amount, and customers disagree on how easily it rinses out.
13 reviews for Douxo S3 SEB Shampoo, Contains 0.5% Ophytrium, Odor Control & Seboregulating, for Oily to Flaky Skin, Seborrhea, for Dogs and Cats, 6.7 fl. oz. (200mL)
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$22.99
Sarah O –
Great value
Great product, my youngest fur baby was having stinking issues. And we were having a hard time figuring it out. Normal bath products did not work. There was nothing visible on her skin. So calling the vet was finally option. They said she might just be producing extra sebum and suggested this product. Major game changer. Ended up getting the foam to bc she really hates baths. But it has helped her have less baths, and less excess oil so the stink has tuned down. We brush her weekly still. But she isn’t taking weekly baths like before lol
Katie Daniels –
Amazing for cat dry skin and dander!!
I have an older cat whoâs about to turn 12. For the last year, her skin on her back has gotten drier and drier. I tried brushing it often, bathing her often with multiple different shampoos, putting a little bit of coconut oil on her back, and it always came back within a few days. It was BAD. Her dander was coming off in huge flakes and combing it just spread it all around. I wish I could have taken a before picture to prove just how bad it was.I took her to the vet and all her vitals were fine, so they suggested to first try this shampoo and mousse. I washed her pretty throughly twice, and the second time I let the shampoo sit on her coat for 5 minutes before rinsing, like the instructions said. Once her coat dried, I applied the mousse from the same line. I comb the mousse through to make sure it gets all the way to her scalp. After just the first use, all the dander was gone and her cost was super soft and healthy. Iâve been applying the mousse 3 times a week. Itâs been two weeks and her coat is still soft and dander free! Iâm so happy this helped because I was so worried about her. Now thereâs also less dander flakes around the house! 10/10 recommend and also veterinarian recommended!
Leda –
It works for dog allergy sores
My dog has allergies. Get small sores on his back. The shampoo gets rid of the sores after using once a week for 4 weeks. Wonderful product.
Laura –
Great for Short-Hair Dog w/ Slick Coat – Didn’t Work Well for Fine-Hair Cat
I bought this for both of my senior pets that have skin and coat issues after having mixed experiences with similar shampoos.The shampoo works very well for my dog that has dry/ irritated skin and a short, slick coat that tends to get greasy quickly. She has been noticably less itchy, has less dry skin flakes, smells better for longer, and her hair no longer builds up oils as quickly. She went from needing a bath once every two weeks to once a month.That being said, it did not work well for my senior cat. He struggles to groom himself and his skin is often irritated, which has resulted dead skin build up and his fur being generally greasy. (All of this despite frequent brushing and cleansing wipes). Similar shampoos have worked really well for him in the past, but this one seems to have left a residue on his fur that left him more greasy than he was before the bath.Overall I would recommend this if you have a dog with a slick coat facing similar issues as ours. The shampoo is a bit pricey for the amount you get, but it does go a long way and has helped our dog tremendously.
Scarlett Sullivan –
Gets rid of the greasy oil
My homeopathic vet actually suggested this product, and normally they only say natural products. But, he thought at times you may have to use a more aggressive product to get seborrhea contained. The shampoo appears to lessen the oil in the skin, without hurting any other less affected places on the body. This has a light scent, but its not heavy or irritating. The dog felt less itchy, and less oily after the bath. This is a product that costs more, but if your dog has seborrhea I can say it improved the skin on my dog. Nothing else was working. The most important comment I have is to read the instructions on the bottle. Your dog will most likely not get relief if you do not leave the shampoo to sit on the coat the suggested length of time. I know! This is not the first time I have bought this product. If you leave it on and rinse immediately, you will not see results.
DS –
Worth every penny!
Our 13 y/o large Goldendoodle has had seasonal skin allergies since he was a puppy- but just recently it became worse due to age. I didnt realize how dull his coat had become until we saw the results of his first bath with this shampoo! The first thing I noticed about the shampoo was how easy and well it lathered.. it feels so creamy.. like velvet! It must have felt great on his skin because he stood so still during the bath like he was enjoying every second! Rinses beautifully and after drying his fur was so soft and fluffy looking. And there was no âwet dogâ smell afterwards! Just great smelling! Nothing like any shampoo weve used .. and in 13 yrs weve used alot (mostly mild oatmeal type). The rough scabby areas of his skin seem to have decreased 50%. We will definitely keep using this. Itâs on the expensive side but definitely worth it!
Kindle Customer –
Effectiveness
Has helped my dog get relief. Cleans well
Sarah Naylor –
Ehhh
This is probably a great shampoo but did not help my dog at all. If anything made my dogs skin worse. A chlorhexidine shampoo is what my dog needed. The ingredients in this didnât help.
Monica G. –
It does what it says. Excellent product to treat and soothe seborrheic dermatitis in doggies
Jana Moll –
Das Produkt tut Haut und Fell sehr gut.
Amazon Customer –
Very easy to apply and smells really nice. So far dogs skin seems to be settling down a bit after one bath and use of mousse, with no signs of any irritation from the shampoo. Hopefully with weekly bathing skin will improve a lot more.
Dilka –
ExpensiveBut does the job
Lucylou –
This cleared my dogs skin up when he had a thorn in his leg that he decided to âoperate on himselfâ before I checked him. The smell isnât overpowering but a nice clean fresh scent no irritation and easy to use. My only criticism would be the price for the size of the container it is not great value for money especially if you have a very furry or large dog although it is a quality product if you had to use it daily for a few weeks or months it would be very expensive. Hence the 4 stars rather than five.