Douxo S3 Seb Shampoo, Contains 0.5% Ophytrium, Odor Control & Seboregulating, For Oily to Flaky Skin, Seborrhea, For Dogs and Cats, 16.9 fl. oz. (500mL)
$38.99
Price: $38.99
(as of Oct 31, 2025 05:17:25 UTC – Details)
Formulated to remove excess sebum, oils and flaky skin buildup. Helps reduce dandruff and deodorize. Moisturizes and detangles the fur to leave the coat soft and shiny. DOUXO is the #1 non-prescription topical brand used and recommended by U.S. veterinarians for dogs and cats with seborrheic dermatological diseases.
Package Dimensions : 7.52 x 3.43 x 2.01 inches; 1.3 Pounds
Item model number : D98620E
Date First Available : May 5, 2021
Manufacturer : Douxo S3
ASIN : B09478VXZP
Best Sellers Rank: #13,835 in Pet Supplies (See Top 100 in Pet Supplies) #117 in Dog Shampoos
Customer Reviews: 4.6 4.6 out of 5 stars 568 ratings var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
DOUXO S3 SEB Shampoo is for dogs or cats with oily to flaky skin
Helps control dandruff and odor by normalizing sebum production while hydrating the skin
Detangles the fur and leaves the coat soft and shiny
Clinically proven in dogs to reduce dandruff, excess sebum, and unpleasant odors
For best results use with DOUXO S3 SEB Mousse
Customers say
Customers find this shampoo effective, with one mentioning it works best when used with the mousse. The product receives positive feedback for its scent, skin gentleness, and quality, with customers noting it’s gentle on skin and helps with itchy, greasy conditions. They appreciate its softness and longevity, and one customer specifically mentions its brightening effect on their Great Pyrenees’s fur. Customers disagree on the value for money.
11 reviews for Douxo S3 Seb Shampoo, Contains 0.5% Ophytrium, Odor Control & Seboregulating, For Oily to Flaky Skin, Seborrhea, For Dogs and Cats, 16.9 fl. oz. (500mL)
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$38.99
EG –
The Shampoo That Turned My Greaseball Into a Show Dog
I bought Douxo S3 Seb Shampoo for my bulldog, who had developed a persistent case of oily seborrhea that made him smell like a forgotten gym sock and look like heâd been dipped in fryer grease. Weâd tried everythingâmedicated wipes, antifungal sprays, even vet-prescribed shampoos that smelled like chemical warfare. Nothing worked for more than a day. Then came Douxo.The first thing I noticed was the texture: thick, creamy, and easy to lather. It didnât run off his coat like water on wax. I massaged it in and let it sit for the recommended 10 minutes, which he tolerated surprisingly well thanks to the mild scentâclean, almost herbal, and not remotely medicinal. After rinsing, his coat felt softer, less greasy, and the usual sour odor was gone. Not maskedâgone.By the third wash, the transformation was undeniable. His skin wasnât flaking, his fur had a matte finish instead of a slick sheen, and he stopped scratching like he was auditioning for a flea circus. Even the vet was impressed. The shampoo didnât just cleanâit recalibrated his skin. The Ophytrium ingredient seems to work like a skin whisperer, calming inflammation and restoring balance without stripping natural oils.Iâve since used it on my other dog, a golden retriever with seasonal dandruff, and it worked just as well. The bottle lasts longer than expected, and the formula rinses clean without leaving residue. Itâs become a staple in our grooming routine, and I now recommend it to every pet owner I meet at the dog park.
Olivia –
This shampoo is a great help!
This shampoo hasnât âfixedâ my Goldenâs stinky, oily, itchy, flaky coat, but it has helped SO much!First of all, itâs so gentle and soothing that I can use it more often than normal shampoo to take care of his stink without making the itch and flakiness worse, which is a win on its own. But a major plus is that I really think it has helped with improving the overall health of his skin and coat. Heâs so much less itchy after a bath now than before (typically itâs the opposite) and the scent of the shampoo really takes away that stinky dog smell. He still gets stinky and oily quickly, especially compared to other dogs that donât have this problem (seriously, you can smell him after just 5-6 days), but itâs better than what it was (the freshly bathed, clean dog smell used to only last 3 days tops before, so any extension is a win). Also, no more hot spots since starting this shampoo! To clarify, he never had a huge issue with hot spots like some dogs do. At its worst, we would find one or two a month just starting, but they never got really inflamed like I know some dogsâ do, so if your dog really struggles maybe take that with a grain of salt. This product is so gentle and soothing though, I know it wonât make skin irritations worse.We wet his fur throughly and work this shampoo in really well, starting with the areas that get the most oily, flaky, and itchy. We do avoid the face with this, never really going past the ears. Then we let it set for the entire 10 minutes. We like to give him a lick mat while he waits. Then we rinse, leaving his problem areas for last. We can give him a bath every two weeks with this shampoo (we never would have done more than every 3 wks with a normal shampoo, even though with the smell, he could use a bath every week).
Keri Fastenau –
Works great for dry skin
Worked great for my dachshundâs dry skin
Lisa Zettler –
It Works!
Very slight scent, seems to keep the âwet dogâ smell away and keep my dogs smelling better for longer. I will say, you have to use it as directed to achieve the full benefit.
Annika –
Idk if it helped
I donât know if itâs helping my dog. Our vet said to start using it when we took our dog to the vet for dry skin and hair loss. He still has dry skin and hair loss but he smells better, so heâs cleaner.
Elena –
Happy dog
Great shampoo. My dog, a chocolate lab, has extremely sensitive skin and all the shampoos I tried before left her skin flaky and itchy. This one works amazingly.
Haku –
Great for big dogs, dries well, and gentle on skin
Iâve tried a bunch of different medicated shampoos for my dog because he is prone to skin infections. This shampoo is very thick so you get more fur coverage per pump. The pump dispenser is a useful design too. This has lasted much longer than other medicated shampoos that sometimes only last a couple baths because itâs too thin. This one also does not have a gross medicated smell and has been very brightening for my Great Pyreneesâ fur. It also doesnât have an overwhelming scent itâs just neutral. Great value and size as well as effective for my sensitive skinned guy!
Jennifer –
Highly recommend
Helped my yorky when the vets couldn’t! Highly recommend
Eddiezz –
Na
MAURICIO FIERRO –
Es un shampoo para la piel de mi perrita que padece de ictiasis
Amazon Customer –
Itâs amazing smell and make my dogs smell so good after the shower. It makes the fur soft too which I love.