Advantage II Large Dog Vet-Recommended Flea Treatment & Prevention | Dogs 21-55 lbs. | 4-Month Supply

Price: $50.98
(as of Nov 02, 2025 15:48:50 UTC – Details)

Advantage II Large Dog is the vet-recommended prevention and treatment of flea and lice infestations in dogs. Advantage II Large Dog flea treatment and prevention kills adult fleas, flea larvae and flea eggs to deliver total flea protection to your dog or puppy. In fact, within 12 hours of application, Advantage II Large Dog topical treatment gets straight to work killing fleas through contact, so they don’t have to bite your dog to die.
This 30-day treatment effectively breaks the flea life cycle, controlling existing flea and lice infestations and preventing further infestations all month long. Fleas not only cause discomfort; they can also pose other health risks. Monthly use of Advantage II Large Dog is important to protect your dog against fleas that may cause transmission of tapeworms in dogs, Flea Allergy Dermatitis and flea bite anemia.
That’s why Advantage II topical, spot-on formula makes application simple – going on in seconds. It’s easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that Advantage II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects.
Advantage II Large Dog flea and lice protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh 21 to 55 lbs. to use Advantage II Large Dog.
For the ultimate convenience in care, Advantage II Large Dog is available over the counter – no prescription needed. And, you can stock up with a subscription for regular doorstep deliveries so you never miss a monthly treatment. Once Advantage II Large Dog is applied, your dog is ready to get right back to exploring his favorite places – from the backyard to the dog park.
Advantage II Large Dog is a trademark of Elanco or its affiliates.
Is Discontinued By Manufacturer ‏ : ‎ No
Product Dimensions ‏ : ‎ 6.5 x 1 x 4.25 inches; 0.63 ounces
Manufacturer recommended age ‏ : ‎ 1 month and up
Item model number ‏ : ‎ 86336707
Department ‏ : ‎ Flea & Tick
Date First Available ‏ : ‎ March 5, 2011
Manufacturer ‏ : ‎ Elanco US Inc
ASIN ‏ : ‎ B004QRFJA4
Best Sellers Rank: #6,508 in Pet Supplies (See Top 100 in Pet Supplies) #39 in Dog Flea Drops
Customer Reviews: 4.5 4.5 out of 5 stars 4,547 ratings var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });

Vet recommended flea treatment and prevention for dogs at weighing 21 to 55 lbs., at least 7 weeks of age
Kills adult fleas, flea larvae and flea eggs for total flea prevention and treatment
Same-day effectiveness, kills fleas within 12 hours of application and keeps working for 30 days
Easy-to-apply topical treatment, no prescription needed
Fragrance-free formula, waterproof after 24 hours