Nutramax Laboratories Denamarin Liver Health Supplement for Medium Dogs – With S-Adenosylmethionine (SAMe) and Silybin, 30 Tablets
$42.99







Price: $42.99
(as of Oct 27, 2025 22:48:50 UTC – Details)
Denamarin coated tablets containing SAMe (s-adenosylmethionine) and silybin can be used in dogs of all sizes to help support healthy liver functions. In addition, research has shown the administration of Denamarin coated tablets to be safe for dogs. Denamarin Liver Health Supplements are brought to you by Nutramax Laboratories Veterinary Sciences, the #1 veterinarian recommended supplement company. *Source: Survey conducted among small animal veterinarians who recommended animal supplements.
Is Discontinued By Manufacturer : No
Product Dimensions : 5.6 x 3.6 x 1.4 inches; 1.6 ounces
Item model number : DENAMARIN225
Date First Available : January 25, 2008
Manufacturer : Animus, Inc.
ASIN : B0011XOXG2
Best Sellers Rank: #2,505 in Pet Supplies (See Top 100 in Pet Supplies) #77 in Dog Supplements & Vitamins
Customer Reviews: 4.6 4.6 out of 5 stars 4,776 ratings var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
Liver Support for Dogs: Denamarin is the #1 veterinarian recommended liver support supplement for dogs. This supplement contains s-adenosylmethionine (SAMe) to help increase levels of the antioxidant glutathione – one of the liver’s main detoxifying agents
High-Quality Ingredients: The Silybin found in Denamarin has shown better absorption by dogs than the standardized milk thistle extract found in many other products
Support Your Dog’s Liver Health: The liver is one of the most vital organs in your pet and is responsible for removing toxins, storing energy, aiding digestion, and supporting the immune system
From the #1 Veterinarian Recommended Supplement Company*: Nutramax Laboratories Veterinary Sciences has been a leader in pet health for over 30 years, and provides supplements to support joint health, digestive health, and overall wellness
Backed by Science: Nutramax Laboratories Veterinary Sciences supplements are veterinarian formulated with high-quality ingredients to ensure your pet is receiving a safe supplement
Customers say
Customers find the liver supplement effective at lowering liver lab results and bringing enzyme levels back to normal, particularly for dogs with liver shunts and elderly pets. The product receives positive feedback for its quality and value, with customers appreciating its reasonable price. Customers disagree on the ease of administration, with some finding it easy to swallow while others report their dogs refuse to take it. The pill size receives mixed reviews, with several customers noting it’s too large for their medium-sized dogs.
8 reviews for Nutramax Laboratories Denamarin Liver Health Supplement for Medium Dogs – With S-Adenosylmethionine (SAMe) and Silybin, 30 Tablets
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$42.99
The Sween –
Vetri-Liver and Denamarin is working!!!
Vetri-Liver and Denamarin is working!!!My story: Our dog is a 12ish Jack Russell mix. In August 2017, he was off. Not himself. Bloodwork and ultrasound showed he likely had Chronic Hepatitis. Put him on Denamarin. Bloodwork improved, but still not perfect. Had the vet do a dental thinking that the liver issues could be from bad teeth. They put him on a preventative antibiotic. 1 week after the Dental he spiked a 106 fever. He was ultimately put on IVs with a different antibiotic. Fever came down, felt better. Noticed that he had developed a licking issue after eating which was new. Fever slowly started to climb back upward. At 104 he was put back on IVs, taken off of all antibiotics in an attempt to get the bacteria to flourish and to isolate it. The only problem was that once he was off of the antibiotics his temperature went normal never to return. Eating throughout this has been difficult. Turning down filet mignon or whatever concoction I could come up with to tempt him to eat. I had pointed out to the vets (lots of them) that the antibiotics warned against liver and kidney issues. Everyone poo poo’d that. Well, it turns out that his liver couldn’t process them.I took him home on Christmas Day from the vet hospital. They wanted to do a liver biopsy, but I rejected it. He already looked like warmed over death. Wasn’t eating a thing in the hospital. They would have had to put him back on antibiotics. – And there was no clear indication that the liver was the origin of the problem, and could just be a secondary to another issue like heart disease (he does have a small heart murmur, but his heart is working sufficiently), cancer, etc. Even if we knew exactly what the liver diagnosis was, the treatment wouldn’t be much different: Diet, supplements and potentially prednisone (which is hard on the liver as well – catch 22)At home, he was a new dog. He started eating. I researched every liver diet, and started with a very bland, home-cooked meal. I noticed that if I added a hi-end kibble to his diet, there would be more licking (licking surfaces like the carpeting). I read where compulsive licking is often intestinal distress. I’m not convinced that he also didn’t have some kind of gastric issue, like gastric ulcers, or other intestinal issue, perhaps because of the liver or maybe even driving the liver problem.It is the end of April 2018, and he is doing well. I started him on Vetri-liver in the AM a couple of months ago with a breakfast of eggs, cottage cheese, oatmeal, rice, and chicken/turkey or beef). The Vetri-liver isn’t extremely palatable, but I just cut it in pieces and put it in meat or cheese, and it will go down. Since I don’t have a firm diagnosis for the liver problem, I looked for zinc and anti-oxidants to help the liver even if he had a copper retention problem. Zinc is supposed to offset copper in your diet. It also has some other supplements that he may need.Afternoon, he gets his Denamarin tablet (2 hours after the last meal) and 1 hour before dinner.Supposedly vegetable protein is better for dogs with liver disease. So I came up with some treats that also helped, especially in the beginning when getting him to eat was hard. I fill a turkey pan with: eggs, meat, carrots, sweet potatoes, tofu, wheat germ, peanut butter, coconut oil, and enough oats and a little bit of flour to make a cookie dough. The secret ingredient is a little bacon grease and bacon for palatability. Yes, bad, but makes the difference between this going down the hatch. These can be a mid-day snack, or actually a small meal if we are out hiking, etc. I bake them on cookie tins like brownies, cut them into squares, put them in baggies, and throw them in the freezer. This way they stay fresh.Dinner is rice/oatmeal/sweet potatoes/pumpkin or yams mixed with eggs/chicken/turkey/beef along with some well-processed veggies.I’m not convinced that I’m feeding a balanced diet, so I bought some senior dog vitamins that he gets periodically.Slowly the weight is coming back on. Exercise is important, because he is hungry after exercise. So a small walk in the morning before breakfast and walk before dinner really makes a difference with the pills and food going down. As long as he is eating soft, smaller meals, the compulsive licking has stopped.He is energetic, playing with toys, bright on his walks and back among the living. His liver enzymes are not perfect: ALT started at 275 (August 2017), went to 1,800 during the antibiotic reaction and spiked fever, back to 275 and now down to 253 most recently. ALP started at 263, 656 at its worst, and now at 167. I don’t know if I will be successful in getting them to normal ranges, but if I look at his quality of life, it looks pretty good now.I wanted to share my story, because you don’t hear often that antibiotics could almost kill your dog. And…..your dog can come back after refusing to eat anything after dire illness.Considering a backpack Trip!!
Kenny –
Works wonders!
Canât recommend enough for liver health for your dog! I put them in a pill pocket and my dog loves them! This continues to help my pets lab work trend in the right direction. If your looking for something actually works this is it best value for the cost.
Paulette –
Great supplement for dog!
I highly recommend this supplement. I have been using this for a long time for my dog Cookie. Her liver values kept going up and our Vet recommended trying this as a first step to trying to reduce her levels. After using this for over a year I am happy to say that her liver values were reduced substantially by half. So happy I tried this first as it kept our pet healthy and saved us from having to put her through extensive testing.
Célio Silva –
Support for Your Dogâs Liver Health
This supplement is formulated with SAMe and Silybin, ingredients known to promote liver function. My dog seemed more energetic after daily use. The tablets are easy to administer, and I appreciate the vet-recommended quality. A good addition to a petâs health regimen.
Ella –
Good product
I give this to my dog and he’s doing great. For one this is cheaper than purchasing at the vet office. However, for my needs and situation I need to make sure i purchase things of good quality and reasonable prices for such a time as this.
Pitollie –
Great liver supplement
Recommended by my vet. My dog’s liver numbers should have killed her – she ate a ton of Xylitol. She will need to take this for life but it is doing wonders for her.
JoNita –
Great for dog with cushings.
These are a great option for my dog with Cushings. They used to be blue but are now light brown. She takes it like a champ. We get these on autoship.
Amazon Customer –
price
Dog health & price is right.